#01Nov 10, 2026
cs.CV
Continuous 3D Spatial Transcriptomics Reconstruction via Histology-Informed Implicit Neural Representations
Kaito Shiku, Ryoma Bise, Ahtisham Fazeel Abbasi and 4 more
Three-dimensional spatial transcriptomics (3D ST) enables the analysis of gene-expression patterns across tissue depths. However, 3D ST measurements are acquired from discrete 2D tissue sections, which are often sparsely sampled due to high acquisition costs. To address this limitation, we propose a histology-informed multi-task implicit neural representation (HIM-INR) for continuous 3D gene-expression reconstruction from sparse ST observations. HIM-INR jointly reconstructs gene-expression profiles and histological representations using an INR with a shared backbone, leveraging densely sampled histological images as auxiliary spatial supervision. Once trained, HIM-INR predicts gene expression at arbitrary 3D coordinates without requiring histological images. Experiments on two 3D ST datasets demonstrate improved reconstruction over existing methods, particularly as the number of missing ST sections increases.
#02Nov 10, 2026
cs.RO
ForeseeDrive: Future-Token Conditioning for Anticipatory Generative Driving
Shaokai Wu, Xunchu Zhou, Pinzhi Wang and 8 more
Generative driving planners can represent diverse ego futures, but a downstream scorer can choose only among sampled candidates; it cannot recover an absent maneuver. We present ForeseeDrive, which turns future scene evolution into a deployable interface for shaping candidate generation. Rather than reconstructing dense future states or scoring a fixed menu, ForeseeDrive derives query-indexed tokens from logged actor motion, occupancy evolution, route interactions, and TTC margins, and predicts the same token space from present context at deployment. The tokens condition trajectory geometry before candidates materialize. A zero-token-gated residual path and candidate-preservation loss limit unnecessary drift, while a TTC-margin guard targets brittle safe-to-unsafe boundary crossings. Under their respective benchmark protocols, ForeseeDrive reaches 89.2 PDMS on NAVSIM navtest, 0.41\,m average L2 and 0.05\% collision rate on nuScenes validation, and a 76.50 driving score on Bench2Drive. Controlled DiffusionDrive/NAVSIM diagnostics show an exact zero-token no-op, a small aligned-over-shuffled selected-PDM advantage under preservation, mixed oracle-best quality, and localized TTC-boundary failures. Together, the benchmark results and bounded mechanism tests support future-conditioned generation as a practical interface for anticipation. Code is included in the supplementary materials.
#03Nov 10, 2026
cs.CR
GARD: Gradient-Guided Adversarial Representation Defense against Backdoors in Multimodal Contrastive Learning Models
Yuhong Wang, Yujun Cai, Lei Feng and 1 more
Multimodal contrastive learning models such as CLIP are vulnerable to backdoor attacks with diverse trigger structures, ranging from localized patches to globally distributed perturbations, with recent attacks increasingly optimizing these triggers in the representation space. Existing post-hoc defenses based on clean fine-tuning may leave backdoors active, while trigger-inversion methods depend on accurately estimating the attack target and trigger. We observe that backdoored encoders exhibit structure-dependent representation sensitivity: global perturbations preferentially expose distributed backdoors, whereas local patch perturbations are more effective for localized backdoors. Based on this observation, we propose Gradient-Guided Adversarial Representation Defense (GARD), a target- and trigger-agnostic post-hoc defense. GARD optimizes complementary global and local adversarial probes to maximally displace clean-image representations, and then realigns the perturbed representations with detached clean anchors while preserving image-text alignment. The resulting model requires no additional computation at inference time. Across six visual backdoor attacks and two CLIP visual backbones, GARD reduces the attack success rate below 1% in all 12 evaluated attack-backbone combinations while maintaining competitive clean accuracy. These results demonstrate the effectiveness of adversarial representation probing for repairing backdoored multimodal contrastive encoders.
#04Nov 10, 2026
cs.CV
UGG: Unified Generative Geometry Model
Amani Kiruga, Zhiyi Li, Ruojin Cai and 4 more
Understanding 4D scenes is a core challenge in visual intelligence, requiring models to jointly capture scene geometry, appearance, and dynamics from partial observations. However, existing approaches are subdivided into feedforward models for direct geometric prediction, and generative models for visual synthesis. We introduce UGG, a unified framework for 4D scene understanding that jointly models RGB video and geometric representations such as depth and camera pose. By assigning different noise levels across modalities and time, UGG formulates visual generation and geometric prediction as conditional completion within a single generative model. This flexible formulation enables the model to learn from diverse, heterogeneous datasets with different subsets of geometric and visual annotations. Furthermore, our generative formulation enables inference-time search over multiple plausible scene hypotheses, using geometric evidence extracted from observed RGB frames to improve geometric prediction without ground truth geometry. We demonstrate UGG's effectiveness over non-unified baselines across camera-controlled video generation, depth estimation, and camera pose prediction, including in challenging sparse observation settings. Code and visualizations are available at https://ugg-model.github.io/
#05Nov 10, 2026
cs.CV
ViGA-FLAME: Aligning Latent Visual and Geometric Representations for Robust 3D Head Expression Estimation
Wen Hao He, Jiacheng Wu, Jie Chen
Estimating 3D head expression from a single image requires mapping visual appearance to underlying facial geometry. We propose ViGA-FLAME, a two-stage framework that aligns semantic visual features with a structured geometric latent space. First, a Parametric-Geometric Variational Autoencoder (PG-VAE) learns a unified representation of canonical head surfaces and FLAME parameters, supporting both detailed surface reconstruction and interpretable parameter recovery. Supervision on geometry and parameters, together with consistency between the two decoding branches, connects surface detail with parametric structure. Second, a trainable Visual-Geometric Adapter (ViGA) maps features from a pretrained semantic visual encoder into this latent space. Asymmetric attention enables ViGA to align semantic image features from the visual encoder with the structured geometric information represented in the PG-VAE latent space, without altering the original visual stream. By grounding image evidence in this latent prior, ViGA-FLAME enables robust 3D head expression estimation across severe facial deformations and large viewing angles, efficiently improving robustness over competing feed-forward methods.