#01Nov 10, 2026
cs.LG
TorchCurves: Differentiable Parametric Curves
Alex Shtoff
We present TorchCurves, a PyTorch library that treats vector-valued parametric curves as learnable primitives. Its central operation maps batches of scalar inputs to points on curves represented in B-spline or Legendre polynomial bases, with differentiation through both inputs and coefficients. Curve coefficients can be optimized jointly with the surrounding model or produced by another network. The library provides trainable modules, reusable basis modules, and a functional interface, supporting applications ranging from continuous feature embeddings to Kolmogorov-Arnold networks and functional regression. Its implementation combines classical evaluation algorithms with vectorized PyTorch operations, emphasizing readability and maintainability without custom hardware kernels. Timing experiments compare curve evaluation against NumPy and SciPy and KAN training against EfficientKAN across a range of problem sizes. The results illustrate where this generality remains computationally practical and where overhead is substantial. Library is available on GitHub at https://github.com/alexshtf/torchcurves.
#02Nov 10, 2026
cs.LG
When Does the Real Wiring Win? Testing connectome structure-function claims against unmeasured physiology
Yeyuan Liu
Connectome-constrained models are often used to argue that a measured wiring diagram outperforms shuffled or rewired wiring, and hence that structure shapes function. Such comparisons can confound wiring with how the models are tuned: a connectome fixes who connects to whom, not the excitability, gains or plasticity rates the model also needs, and modellers often tune these until the real-wiring model works. We separate three estimands: physiology tuned on the real wiring and transferred to nulls (P1), each wiring tuned on its own (P2), and P2 restricted to physiology consistent with independent data (P3). The biases involved are known in machine learning (under-tuned baselines, inherited weights, winner's curse); we measure what they do to biological conclusions, using synthetic ground truth, placebo nulls and three Drosophila circuit models. Some claims survive every protocol we test: segregated reward and punishment dopamine improves learning, and head-direction topography is required for a persistent bump. Others do not. In the mushroom body, the real Kenyon-cell output wiring beats a cross-subtype identity shuffle by 0.09 under P1 and P2 but loses to it by 0.09 under P3 (95% CIs exclude zero; held-out runs confirm). The verdict is set by the share of alpha'beta' cells among active Kenyon cells, which P1 selects low; at the share implied by imaging (about 44%) the real-wiring model fails to learn, exposing a model inadequacy rather than a deficit of the fly's wiring. In flyvis, P1 penalises a mirrored connectome, which has a constructed solution within 0.07 (median) of the real error, more than a spatially shuffled one in 50 of 50 members; the ranking survives ten-fold longer retraining but depends on the checkpoint at fifty-fold. A credible structural claim needs matched optimisation, data-constrained physiology and a model that still works there.
#03Nov 10, 2026
cs.CV
Medical Image Segmentation: Foundation Model Adaptation versus Task-Specific Training
Emre Kutlusan, Yongmin Li
Foundation models pretrained on large natural-image collections are increasingly adapted for medical image segmentation, in the expectation that they will replace models trained for each task. Most comparisons, however, use data from the training distribution and a single task-specific baseline whose configuration is rarely justified, and therefore provide limited evidence of performance at new clinical sites. It also remains unclear how much of a foundation model must be adapted, and what determines this. We adapted a foundation model, DINOv2, with strategies ranging from tuning only its bias terms to full fine-tuning, and compared it with U-Nets and ResU-Nets trained from scratch. Experiments covered colonoscopy, breast ultrasound and dermoscopy, with testing on held-out data from the training source and on independent datasets from other institutions. The adapted foundation model generalised better on every external dataset. Within the training distribution, the task-specific models remained competitive when training data were abundant, and delineated boundaries more precisely, while the foundation model more often missed small lesions. Only a small fraction of the foundation model required adaptation, and the capacity needed was determined by the imaging domain rather than by the adaptation method. A widely used polyp test set was also found to duplicate images from another benchmark. Foundation-model adaptation is therefore warranted where models must work across sites, with capacity selected on the target domain.
#04Nov 10, 2026
cs.LG
AutoScaffold: AI-Guided Scaffolding for Reinforcement Learning of Language Models
Zijian Zhang, Rizhen Hu, Jiangweizhi Peng and 4 more
Reinforcement learning with verifiable rewards (RLVR) produces rich training experience, yet outcome rewards reduce each attempt to a single number and leave most of this information unused. Training-time scaffolds, such as strategies or hints added to the prompt during training, offer a natural way to turn this information into guidance, but their design and adaptation are largely left to humans and tailored to specific domains. We introduce AutoScaffold, a unified AI-for-AI framework that turns a student's training experience into adaptive scaffolds, with minimal domain-specific information and no human intervention during training. A frozen teacher periodically examines this experience, diagnoses bottlenecks, and designs scaffolds in two forms: (i) strategies shared across a class of tasks and (ii) hints for individual hard tasks, adjusting the content and amount of support as the student learns. The scaffolds are removed at evaluation. We apply the same framework to ALFWorld, search-based QA, mathematical reasoning, and GPU kernel generation. When evaluated without scaffolds, students trained with AutoScaffold outperform those trained with the corresponding RL baselines in all four domains, with gains of 7.2 points in ALFWorld success and 4.0 points in average QA exact match. On GPU kernel generation, AutoScaffold increases the fraction of tasks with a correct kernel that runs faster than the PyTorch reference by up to 5.0 points. On math, our student surpasses QuestA's reported accuracy using approximately one-third as many student training steps. Analyses show that the teacher identifies a different failure in each task class and shifts its scaffolds from step-by-step workflows to targeted fixes as the student improves, and that its revised scaffolds help the student learn more than keeping the previous scaffold or using no scaffold.
#05Nov 10, 2026
cs.CV
Toward Foundation Detection Models via Example-Based Grounding in EM-DETR
Sheethal Bhat, Bogdan Georgescu, Awais Mansoor and 3 more
DeepLearning (DL)-based Computer-Aided Diagnostic (CAD) systems have shown great promise in supporting clinicians, but their performance heavily depends on the availability of large, well-annotated datasets. In medical lesion detection, the scarcity of comprehensive, stan dardized annotations and the heterogeneity of existing datasets limit the development of robust foundation models. In this work, we introduce a novel approach to building a multi-domain foundation model for le sion detection by integrating diverse medical image datasets annotated for both anatomical structures and abnormalities. We first propose a student-teacher training strategy to effectively combine datasets with heterogeneous label spaces, mitigating catastrophic forgetting, and im proving feature learning. In addition, building on our previously pro posed example-based EM-DETR framework, we adapt it to jointly learn from multiple domain-specific datasets, enabling fine-grained, example driven detection across modalities. Our model achieves state-of-the-art (SOTA) results, with image-level AUC scores exceeding previous SOTA by 1% point on four key findings in CXRs. We achieve a leading mAP50 in CXRs and mammography, surpassing EM-DETR trained on a single dataset by 2-3% points. This approach paves the way for scalable foundation models in medical imaging that leverage heterogeneous data while maintaining robust and generalizable performance.