#01Nov 9, 2026
cs.DB
LUCQUE: A lung cancer screening dataset from Québec for reliable AI evaluation
Johanna Topalis, Yannick Lemaréchal, Gabriel Couture and 7 more
BACKGROUND: AI-based tools are expected to play a key role in lung cancer screening (LCS). The evaluation of these tools often relied on private datasets or fragmented public datasets with inconsistent availability of clinical data and expert nodule annotations. This has hindered reproducibility, comparability, and independent assessment of AI tools. To address these gaps, we present LUCQUE, a novel, large, comprehensively annotated dataset derived from LDCT lung cancer screening in Québec, which is accessible for reliable AI evaluation. METHODS: LUCQUE was curated and is hosted on PARADIM, a digital infrastructure supporting DICOM data de-identification, annotation, long-term storage and analysis. LDCT scans and clinical information were combined to a curated collection and complemented by voxel-level, expert-derived pulmonary nodule and cyst segmentations, and Lung-RADS-based lesion characteristics. Key dataset characteristics and statistics were reported, including participant demographics, imaging parameters, radiological findings, and segmented lesion characteristics. Dataset analyses were conducted according to PARADIM's model-to-data approach, in which user code is executed on the platform such that data remains on premise. RESULTS: LUCQUE currently comprises 1,678 LDCT baseline studies from 1,678 participants. Most studies were classified as Lung-RADS 2. A total of 1,776 pulmonary nodules and 60 cysts were annotated, with a median (interquartile range) volume of $89\,(56,\,159)\,\mathrm{mm}^3$ and $1,384\,(589,\,3793)\,\mathrm{mm}^3$ respectively. CONCLUSIONS: Compared to publicly available LCS datasets, LUCQUE currently represents the largest accessible annotated real-world LCS dataset. Access to LUCQUE is provided via a model-to-data approach, enabling privacy-preserving, reproducible, and independent real-world evaluation of AI tools in LCS.
#02Nov 9, 2026
cs.LG
Guiding Data Allocation for Robust Subpopulation Generalization
Zhaoying Pan, Yipei Wang, Shenyu Lu and 1 more
Machine learning models often achieve high average accuracy in the training data while performing poorly on test data due to subpopulation shift. A common data-centric solution is to enforce balanced subgroup proportions, but full balance can be costly, infeasible, and not always necessary. In this work, we study whether balanced training data is the unique optimal configuration for robust subpopulation generalization. We extend a Gaussian feature-model framework to theoretically characterize the performance landscape across general training subgroup distributions. We show that multiple configurations, including substantially imbalanced ones, can perform comparably to the balanced one. We further derive gradient-based directions for adjusting subgroup proportions to improve adjusted accuracy and worst-group accuracy more efficiently. These findings suggest that strategically allocating data offers a more flexible and principled path to robust performance than simple balancing. The code is available at https://github.com/zhaoyingpan/subpop-data-allocation.
#03Nov 9, 2026
cs.LG
Where Does Alignment Emerge and What Does It Mean? A Closer Look at the Platonic Representation Hypothesis
Julia Herbst, Simon Roschmann, Quentin Bouniot and 1 more
The Platonic Representation Hypothesis (PRH) suggests that neural networks are converging toward similar representation spaces. As language models become more capable, their representations are aligning with those of vision models. However, recent work has questioned whether this trend continues to hold for newer language models. Moreover, it has been shown that representation similarity metrics can be confounded by model depth and width, requiring appropriate baselines for interpretation. In this work, we first investigate where alignment emerges between unimodal models across model layers and representation dimensions. Next, we find that the PRH capability-alignment trend persists for newer models as long as the captions are sufficiently clean and informative. Finally, we contextualize cross-modal alignment, introducing unimodal and multimodal baselines on various datasets. Our results show that the cross-modal representational alignment of unimodal models can surpass that of explicitly aligned vision-language models, but remains substantially behind the alignment observed for models of the same modality. Code is available at https://github.com/ExplainableML/prh-closer-look.
#04Nov 9, 2026
cs.LG
$Σ$-LeWM: Learning World Models via S-Information for Robot Control
Xinrui Zu, Michael Przystupa, Zhao Yang and 2 more
World models have increasingly been applied as a model-based control method for robotics tasks such as manipulation and locomotion. While early world model architectures relied on decoders to prevent mode collapse and learn a predictable latent space, recent works on world models, such as Joint Embedding Predictive Architecture or LeWorldModel, increasingly aim to learn embeddings without a grounding decoder, utilising only a latent forward dynamics predictor and a stabilising entropy term. In this paper, we set out to demonstrate that the further introduction of two additional latent losses to LeWorldModel, a backward dynamics predictor and an inverse dynamics action predictor, enforces further structure on the latent embedding, leading to further gains in both performance and planning efficiency. These are critical properties for improving the applicability of such methods to real-time model-based control of real-world robots. We demonstrate these gains on standard world model benchmarks and two simulated robot manipulation tasks.
#05Nov 9, 2026
cs.AI
Sage-Taiyi: A Metacognitive Architecture for Scientific Discovery
Weida Wang, Benteng Chen, Yigeng Jiang and 87 more
We introduce Sage-Taiyi, a metacognition-inspired architecture that uses accumulated scientific understanding to guide what to investigate next and how to investigate it. Through explicit monitoring and control, the system revises its understanding of evidence, assumptions, and unresolved questions, then uses these assessments to adapt research targets and select reusable reasoning methods. On Taiyi-Bench, an AI co-scientist ideation benchmark comprising 265 tasks from 50 papers across ten disciplines, Sage-Taiyi ranks first on all eight metrics of historical rediscovery and open-ended ideation, achieving an Overall score of 54.0 compared with 47.9 for the strongest baseline, AI Scientist-v2. It also performs well on two external scientific ideation benchmarks. Five expert-guided collaborations further connect its proposals to experimental and computational validation across chemistry, materials science, and engineering. In chemistry, reaction-condition optimization raises the yield of cobalt-catalyzed carbonylation from trace amounts to 84% and photocatalytic allylic amination from 13% to 69%. These results support metacognitive regulation as an approach to scientific ideation and its progression toward practical validation.