#01Nov 6, 2026
hep-lat
Machine learning for lattice QCD
Gurtej Kanwar, Scott Lawrence, Alessandro Nada and 1 more
Machine learning (ML) methods have been explored as a means of optimizing lattice field theory calculations, with increasing interest in recent years. This chapter gives an introduction and summary to the use of ML methods to optimize lattice field theory without introducing any uncontrolled approximations. We focus on those directions which are clearly established as of late 2025, marking the 50th anniversary of the beginning of the study of lattice gauge theory. This chapter is a contribution to the online book ``Lattice QCD at 50 years,'' (LQCD@50), edited by Tanmoy Bhattacharya, Maarten Golterman, Rajan Gupta, Laurent Lellouch, and Steve Sharpe.
#02Nov 6, 2026
cs.AI
Can Agentic Systems Close the Gap in Radiology with Production AI Tools?
Aubin Charley, Julien Khlaut, Charles Corbière and 3 more
Radiology AI has developed along two paths: specialized models that perform well on narrow tasks but cover few clinical findings, and generalist models that address a broader range of tasks but remain prone to hallucination and inaccurate measurements. Combining the two through agentic systems offers a route towards comprehensive radiology reporting, but published systems are tied to one modality or body part. We describe a radiology agentic framework that standardizes how an orchestrator calls modular tools to produce a structured report, and use it to measure what such a system can do with the tools from FDA-cleared radiology AI devices. Report generation is simulated on a large multi-modality report corpus, with the orchestrator given either a catalog of finding classes consolidated from the cleared devices, each available on the modalities it is cleared for, or an unlimited catalog in which any class can be requested, and planning either from the clinical indication or from the target report. Tool outputs are simulated from the reference report, so the comparison isolates tool availability and orchestration from tool error. With the cleared catalog and the indication alone, the orchestrator recovers under a third of the clinically actionable findings; recovery improves substantially with the unlimited catalog, and further when the plan is written from the target report. Attributing every missed finding to a cause shows that most are classes no cleared device offers for the study's modality, and that a third are classes or tools that were offered and not called. Adding the most frequently missing tools closes most of the gap to the unlimited catalog on held-out reports, whereas a smaller orchestrator with the unlimited catalog gives up the whole gain. Tool availability and effective orchestration are thus complementary constraints on comprehensive AI-assisted radiology reporting.
#03Nov 6, 2026
cs.AI
Generative Latent Priors for Interpreting and Steering Protein Language Models
Daniel Hinjos, Lucía Urcelay
Dominant methods for interpreting large models impose strong structural assumptions. Generative Latent Priors (GLP) are a complementary approach: a diffusion model that learns the distribution of a frozen model's activations directly, imposing no assumptions. We port GLP to ESM-2 activations (UniRef50) and evaluate it at two host scales (ESM-2-8M and -650M), both as a lens for protein representations and as a prior for editing them. Generation quality scales smoothly with depth and compute. As a lens, single GLP "meta-neurons" are the strongest probes of discrete Swiss-Prot concepts at both hosts, beating InterPLM's released SAE features, and lead on continuous properties at 8M though not at 650M; falsification tests show this is mostly concentration, not new information. As an editing prior, the on-manifold correction makes DiffMean steering of three biochemical properties effective and restores on-manifoldness, but only in isolation: re-embedding the sequences actually produced after several rounds of decoding, the structural plausibility is compromised. This is mainly reproduced in additional SAE-based clamping structural steering experiments, where only Helix motif succeeds. The naturalness failure is traced to the rewriting coverage and the decoder rather than the prior, highlighting what the method must clear before it can serve for both discovery-by-editing and discovery-by-exploration. Trained GLPs are released on huggingface.co/collections/HPAI-BSC/glprot.
#04Nov 6, 2026
cs.LG
On the (non-)closedness of the set of ReLU networks
Eloi Martinet, Leon Bungert
We prove that the set $\mathcal{N}_N$ of ReLU networks with one hidden layer and at most $N\in\mathbb N$ neurons is weakly closed in $W^{1,p}(Ω)$, for a bounded connected open set $Ω\subset\mathbb R^d$. Consequently, every coercive, weakly lower semicontinuous energy on this space attains its minimum over $\mathcal{N}_N$. This covers the Deep Ritz method with convex integrands, Sobolev training and Lipschitz learning. Moreover, as the weight decay parameter tends to zero, minimizers of the regularized problem converge, up to subsequences, to minimizers with minimal parameter norm. We also prove that the set of ReLU networks with two hidden layers of bounded widths is not closed in $W^{1,p}(Ω)$ or in $C(\overlineΩ)$. This disproves a conjecture of Petersen, Raslan and Voigtlaender.
#05Nov 6, 2026
cs.AI
Flow-Guided Target-Space Alignment via Path Consistency
Ruizhi Yuan, Zeqiu Yu, Wei Gao and 3 more
Many multimodal alignment problems require mapping a source modality into a fixed space defined by a target modality, where the target space is not merely an intermediate embedding but is used directly for downstream analysis. In this setting, successful alignment should preserve both the global structure of the target distribution and the instance-level correspondence observed in paired source--target training data. Existing objectives typically address only part of this goal: contrastive losses encourage relative similarity, distribution-matching losses improve marginal agreement, and pointwise regression fits each source sample to its paired target without explicitly modeling target-space path geometry. We propose FlowAlign, a flow-guided target-space alignment method that repurposes conditional flow matching as a training-time alignment signal rather than an inference-time transport model. FlowAlign uses the learned flow field to guide the alignment of source-side representations with the fixed target space, encouraging them to preserve paired correspondence while remaining compatible with the global target-space structure. We further provide theoretical analysis showing how FlowAlign helps improve paired correspondence by controlling endpoint accuracy and capturing local target-space geometry. Experiments on synthetic data, paired single-cell multiome benchmarks, and image--text alignment demonstrate that FlowAlign improves instance level correspondence while preserving target-space structure across different modality settings.