#01Nov 4, 2026
cs.CV
Agent-Driven Generative Priors for Pathology Image Synthesis and Segmentation
Sicheng Yang, Rui Tang, Haipeng Zhou and 6 more
Deep learning methods for pathology are constrained by the limited availability and high cost of large-scale pixel-level annotations. Synthetic data can alleviate this limitation, but existing pipelines often lack reliable quality control and remain weakly connected to downstream analysis. To address these issues, we propose a three-stage framework that integrates automated data screening, generative representation learning, and efficient adaptation to downstream tasks. First, we develop a pathology agent system to assess image quality and filter samples, resulting in TCGA-200K, a dataset containing 217,030 pathology patches selected from the public TCGA repository. Second, we train a generative model on the screened data. In addition to image synthesis, its backbone learns structural and semantic representations that can be transferred to downstream tasks. Third, we adapt the pretrained generative backbone to semantic segmentation using a lightweight task-specific head. We further introduce PathSeg-380K, a semantic segmentation dataset with expert annotations for approximately 380,000 cells across 12 cell types. Experiments on multiple pathology datasets show that the proposed framework achieves state-of-the-art segmentation performance. Our code is publicly available at https://github.com/script-Yang/Agent-GenPath.
#02Nov 4, 2026
cs.CV
Occlusion for Free: Detecting Occlusion from the Disagreement Between Two Monocular Distance Cues
Chibueze Praise Onyenweaku, Toyibat Adele, Sikirulahi Opeyemi Abdulkareem and 1 more
Knowing that a pedestrian is occluded is useful to a robot even when the detector cannot recover the hidden pixels, but occlusion estimators are normally trained on occlusion annotations that deployment settings rarely have. We show that occlusion can be read off two distance estimates a camera-only pipeline already computes. Apparent height is largely unchanged by occlusion, because the detected box still spans the whole person; monocular metric depth is pulled toward the occluder, because the nearest surface inside the box is what a depth map reports. Only their ordering matters, so no focal length, stature, or depth scale is needed, provided the depth model's error is close to a pure gain, a condition that can be checked without labels. The score detects heavy occlusion on KITTI with AUC 0.909 (0.888 over all annotated pedestrians, including those the detector misses), requires no training and no occlusion labels, and is not a proxy for range: within fixed distance bands it holds AUC 0.894-0.925 while true distance alone sits near chance. On synthetic CARLA scenes with measured visibility it reaches 0.819, against 0.644 for distance alone. We arrived here after measuring three standard architectural responses to occlusion, depth fusion, occlusion-simulating augmentation, and attention, none of which improved detection outside its training distribution in the configurations we tested, and after finding that a detector trained on German roads loses half its accuracy on self-annotated street scenes in Lagos, Nigeria. Signals that need no local annotation are worth more in settings that benchmarks do not represent.
#03Nov 4, 2026
cs.CV
Trick-or-Treat: Adversarial Evaluation of Multimodal Medical Reasoning with Synthetic Images
Oishi Banerjee, Eujin Lee, Sung Eun Kim and 4 more
We used medical image synthesis to create a challenging multimodal evaluation framework that exposes hallucination behaviors in frontier models. Evaluating multimodal reasoning has historically been difficult because existing medical datasets rarely pair different image modalities, such as radiographs and external clinical photographs. To address this gap, we introduce Trick-or-Treat, an adversarial multimodal medical benchmark that pairs real chest radiographs with synthetic clinical photographs to challenge models' cross-modal reasoning. For each of a wide range of conditions, we created two pairs of images, where the pairs share a single chest radiograph but contain different external photographs. In matched pairs, the chest radiograph and photograph both contain findings suggesting the same disease (e.g., varicella pneumonia suggested by lung opacities and crusted skin lesions seen in chickenpox). In mismatched pairs, the photograph depicts an alternative clinical finding that would not lead to the same unifying diagnosis (e.g. replacing crusted skin lesions with ordinary acne). Synthetic photograph generation allows clinical findings to be varied while the person's features and photographic setting stay consistent, reducing confounding. In an investigation of three frontier models, we found that models hallucinated clinically significant photograph findings in 45-57.5% of mismatched pairs, up from 25-37.5% for the same photographs shown alone. When faced with mismatched pairs, models tended to ignore mismatches and instead hallucinated findings that better matched the radiograph (e.g. misreading acne as crusted skin lesions to justify diagnosing chickenpox). Trick-or-Treat both demonstrates concerning error pattern in frontier models' medical reasoning and provides a proof of concept for the use of synthetic images in adversarial multimodal evaluation.
#04Nov 4, 2026
cs.CV
Dynamical State-Space Diffusion for Spatiotemporal Prediction
Woojun Lee, Hankyeol Kim, Pilsung Kang
Diffusion models for temporal prediction typically corrupt each future frame with independent noise, leaving temporal dependence entirely to the denoiser. We propose Dynamical State-Space Diffusion (DSSD), which learns the temporal structure of the corruption process itself. DSSD builds a temporal kernel from the damped oscillatory modes of a stable diagonal state-space model, whose learned decay rates and frequencies let the corruption capture multiple timescales and oscillatory correlations, while the denoiser architecture remains unchanged. Running this model on a finite clip, however, requires the state before the first frame, which is unobserved; starting from a zero state leaves the early frames with less noise than the diffusion schedule prescribes. We avoid this by using the Cholesky factor of the model's stationary covariance as the temporal operator. We prove that this operator is causal, exactly invertible, keeps each frame's noise variance equal to that of standard diffusion, and reduces to the identity at the clean end of the process, and that it is exactly the Kalman innovations form of the state-space model. The denoiser is trained to predict the temporally correlated noise, and sampling removes and reapplies the temporal mixing at each step. On scientific-field and robot-video datasets, DSSD outperforms diffusion baselines that share its denoiser, and the evolution of its learned modes during training shows that the temporal operator adapts to each dataset.
#05Nov 4, 2026
cs.RO
Perceptive Humanoid Motion from Simulation
Siyuan Hu, Abulikemu Abuduweili, Yue Meng and 5 more
Humanoid robots have the potential to automate a wide range of physical tasks. Progress toward generalist humanoid autonomy, however, remains constrained by a data bottleneck: mapping pixels and free-form language to low-level joint commands requires paired supervision, and no corpus of such data exists at sufficiently large scale. Some approaches rely on human teleoperation and wearable capture devices, which require at least an hour of human time to produce an hour of data. We present HALO, a humanoid autonomy system powered by a pipeline that synthesizes vision-language-motion data across a thousand procedurally generated homes. The corpus scales with compute rather than human labor. HALO acquires a repertoire of physical skills, including sitting on chairs, navigating to named objects, stepping sideways through half-open doors, crouching and crawling beneath tables, and pushing boxes. It orchestrates these skills to solve composite, long-horizon tasks. Without ever seeing a real home during training, HALO transfers zero-shot to the physical world, achieving a 91% success rate across 360 trials in six unmapped real-world environments. See https://apple-aiml-research.github.io/ml-halo/ for code and videos.