#01Nov 5, 2026
cs.LG
Towards interpreting any residual stream direction by scaling activation inversion
Celeste De Schamphelaere, Juan J. Vazquez, Ari Spiesberger and 4 more
To interpret a direction in a language model's residual stream, we can look for text that strongly activates it. But when such text is found by scanning a corpus, it is limited to what that corpus contains. We develop Maximally-Activating Example Metamodels (MAEMs), language models which map residual stream directions from a subject model to text exemplars that strongly activate those directions. Our objective is to maximise the cosine similarity of a supplied residual stream direction with the activations of the text generated by the MAEM. This label-free RL objective helps to scale MAEMs on diverse sources of residual stream directions. Empirically, we find the resultant metamodel produces informative exemplars: a Qwen3.6-27B MAEM inverts held-out activations better than corpus search or a natural-language autoencoder (NLA), beats corpus search (at 10M tokens) on a majority of held-out languages/domains, and activates 89% of held-out SAE features. It also identifies concepts behind steering vectors about as well as NLAs, recovers the payloads of LoRA backdoors more often than corpus search, and can even verbalise some model workspace inner monologue. Unlike explanations produced by other metamodels (e.g. NLAs), MAEM exemplars can be verified with a forward pass on the subject model, making the MAEM objective a grounded alternative for scaling the training of metamodels.
#02Nov 5, 2026
cs.CL
MedGraph: Maintaining Patient State with Graph Memory for Long-Term Medical Dialogue
Donghua Zhang, Zizheng Wang, Ze Dong and 2 more
LLM-based medical assistants that follow a patient across visits need a memory that keeps the patient's clinical state correct as it changes. We examine the errors of five memory systems on longitudinal medical dialogue and find three recurring causes: the retrieved evidence gives an outdated state, includes another person's health facts, or lacks a safety fact the answer depends on. We present MedGraph, a graph memory built for these three cases. Construction extracts dated facts from each session, attributes each fact to the person it describes, and links medication, diagnosis, and measurement records into chains that keep earlier states. Retrieval ranks the patient's chains as units, reads each chain at the time the question asks about, and adds the original dialogue text; a patient profile lists every recorded safety fact with every question. On MedMemoryBench, MedGraph has the highest overall accuracy with both a GPT and a Qwen backbone, 10.5 and 10.4 points above the strongest of five baselines, with efficient memory construction and answering in the GPT setting.
#03Nov 5, 2026
cs.LG
On the limitations of molecular representations
Acer Blake, Fergus Imrie, Charlotte M. Deane
Molecular representations such as fingerprints and learned embeddings play a central role in cheminformatics and small-molecule machine learning. They serve as the primary input for a diverse array of tasks, including clustering, dataset splitting, and virtual screening, yet their evaluation is often limited to downstream model performance on narrow benchmark tasks. We carried out a systematic investigation of the quality of molecular representations, finding that none of the state-of-the-art molecular embedding models capture graph structure, 3D shape, or ADMET endpoint similarity better than fingerprints or physicochemical descriptors. However, classical fingerprints also revealed their own material limitations. For example, we show that depending on the representation, between 225M and $\sim$4B molecules have non-unique representations in the 10.8B Enamine REAL database, with implications for virtual screening. Our findings provide an insight into the current limitations of molecular representations, outlining future research directions for the development of more robust encodings of small molecules.
#04Nov 5, 2026
cs.AI
SwarmEvolve: Latent Agent Swarms for Evolutionary Discovery and Optimization
Qile Jiang, George Em Karniadakis
LLM-guided evolutionary search uses AI agents to improve programs for mathematical and computational problems by iteratively refining solutions and combining high-scoring methods. However, the process is often slow because the LLM generates a long textual chain of thought for each round and must repeat this generation many times to maintain population diversity. We present SwarmEvolve, a framework in which hundreds of low-cost agents per round work in swarms, reason in latent space without decoding to text, and share information by passing KV caches. Each swarm studies the problem from a different angle. A novelty filter keeps the most distinct agent ideas by directly measuring the distances between the agents' hidden state vectors. Crossover of ideas happens naturally in latent space, as a summarizer agent receives the combined KV caches of all swarm members. On 21 problems in mathematical discovery and scientific computing, SwarmEvolve gets the highest average score and needs a median of only 3 to 8 minutes to reach the best scores that other state-of-the-art frameworks reach in 60 minutes. On several problems, SwarmEvolve with Qwen3 8B improves on the solutions that AlphaEvolve first found with frontier LLMs. Our work shows that agent swarms that communicate in latent space offer a fast, low-cost approach to program search for scientific problems.
#05Nov 5, 2026
cs.AI
The Power of Meta Access in the Software of the Future --- Demonstrated on LLM Chat UIs and Chat AI
Julian Kunkel, Ali Doosthosseini
Chat remains the default surface for many large language model (LLM) tasks, even as agentic tools such as OpenCode excel at coding and automation. Yet the model sees the current dialogue but not the workspace around it. We explore meta access---giving the assistant a structured, permissioned view of the interface itself and propose a ladder of levels: feature tutoring; metadata, settings, and preference access; retrieval over summaries and messages, confirmed mutation, and full orchestration. Meta access can turn a chat client from many screens into one entry point for finding, navigating, organising, and operating it, while raising risks around grounding, privacy, prompt injection, and trust. General-purpose agentic harnesses are runtimes; because they can change their own settings, meta access becomes reflexive and needs a separate control-plane boundary. We ground this in the Meta Chat prototype of the Chat AI client. It builds bounded context from, e.g., summaries, settings, and relevant messages; links references to conversations, topics, and personas; supports confirmed, reversible changes; offers a browsable tutorial library; and recommends personas as user-started conversations. By exposing application state in structured form, meta access can extend screen readers from widget descriptions to semantic workspace operations. Meta access thus turns chat from a window onto one conversation into a control layer for the whole workspace, extending chat toward agentic capability without surrendering user control. As assistants become embedded in IDEs, dashboards, office suites, and operating systems, AI-era interfaces should expose a structured, permissioned model of their state and capabilities, ideally by opening their existing metamodels through a debugger-like interface.