#01Nov 4, 2026
q-bio.NC
Learning Time-Varying Connectomes for Stable Behavior Across Development
Christof Fehrman, Jacob J. Morra, Eva A. Naumann
Neural circuits must maintain functionality to drive effective behavior while their size, topology, geometry, and intrinsic dynamics change across development. To model developing visuomotor circuits and behavior, we investigated whether a single compact generative encoding could produce functional recurrent controllers across such changes. Building on the HyperNEAT algorithm, we represented this program as a compositional pattern-producing network that received developmental time as an input to generate age-specific connectivity. The developmental substrate prescribed neuronal birth, position, sensory organization, and intrinsic time constants. We tested this approach using two geometrically distinct developmental substrates and two visuomotor tasks: optomotor responses and phototaxis. Controllers optimized at only the initial or mature substrate generally failed when evaluated at other ages. In contrast, controllers optimized across multiple developmental snapshots maintained substantially higher and more consistent performance across trained and unseen ages. Optimization at only three developmental snapshots was often sufficient to produce effective behavior across the tested developmental interval. The resulting connectomes changed substantially with age and did not converge on a single trajectory of sparsity or connection-weight statistics. Controllers also differed in whether they relied on neurons born later in development. These results demonstrate that a shared spatiotemporal time-varying connectivity program can produce recurrent neural networks that preserve behavior across substantial developmental changes. Together, these results provide a framework for studying how functional stability can emerge without requiring structural or dynamical stability.
#02Nov 4, 2026
cs.CV
Trainspotting: Learning Object-Centric 3D Reconstruction from Found Photos
Hanyu Chen, Noah Snavely
State-of-the-art feedforward reconstruction models perform poorly on in-the-wild object-centric photo collections. They are trained largely on single-session object captures whose images vary in viewpoint while the object and its environment remain nearly fixed. Public photo archives contain a different form of multi-view data. They hold found photos of the same object or design: photos taken independently by many people across years, environments, cameras, and sometimes physical units. In this work, we introduce Trainspotting, a dataset of 12,068 objects and 311,886 photos from Wikimedia Commons. We reconstruct each object to recover camera poses, multi-view stereo depth, and object masks. We categorize the objects into three regimes: objects fixed at one site, objects that move between sites, and designs shared by many physical units. Evaluating recent feedforward reconstruction models on Trainspotting shows that they fail most severely in the last two regimes. Fine-tuning VGGT-$Ω$ on Trainspotting significantly improves camera pose, depth, and 3D geometry on held-out objects. We observe similar improvements on the independent NAVI in-the-wild benchmark, which contains photos of each object in different environments. Performance on conventional benchmarks remains largely unchanged.
#03Nov 4, 2026
cs.AI
BEAKER: An Expert-Curated Benchmark for Embodied Brains in Self-Driving Chemical Laboratories
Fei Lin, Tengchao Zhang, Ziyang Gong and 15 more
Self-Driving Chemical Laboratories (SDCLs) are moving chemical experimentation toward embodied automation, where machines must perceive laboratory scenes, reason about experimental states, and act under physical, procedural, and safety constraints. Although Multimodal Large Language Models (MLLMs) are increasingly considered as embodied brains for such systems, existing laboratory benchmarks mainly focus on safety, anomaly detection, or general scientific understanding, leaving their execution-oriented embodied capabilities underexplored. To fill this gap, we introduce BEAKER, a Benchmark for evaluating Embodied Actionability, Knowledge, Experimentation, and Reasoning in SDCLs. BEAKER contains 1,000 expert-curated question-answer samples across 11 image and video task types, covering key judgments required for chemical laboratory execution, including affordance grounding, trajectory planning, equipment, state, and safety recognition, apparatus setup, operation and step reasoning, and temporal procedure reasoning. All questions and annotations are manually created and reviewed by chemistry and embodied Artificial Intelligence (AI) experts, without AI-assisted generation or annotation. We evaluate 28 general-purpose, science-oriented, chemistry-specialized, and embodied MLLMs in an offline, single-turn setting. Results show that current models can follow coarse experimental procedures in videos, but still struggle to ground actions into operable regions and feasible trajectories, to recognize fine-grained laboratory apparatus, states, and safety norms, and to order steps in mid-length procedures. BEAKER thus reveals a clear gap between coarse procedural understanding and the precise, action-grounded perception required for laboratory execution, providing a diagnostic benchmark for future MLLMs in SDCLs.
#04Nov 4, 2026
cs.CL
Persona Perspectives: Adopting Viewpoints Reorganizes Representations in LLMs
Austin C. Kozlowski, Avital Mintz, Madison Lee
Common methods for monitoring features in large language models (LLMs) such as linear probes and sparse autoencoders (SAEs) assume that features maintain a consistent representation across contexts. LLMs, however, can flexibly adopt different perspectives or "personas" that suggest different underlying systems of conceptual relations. In this paper, we examine whether prompting an LLM to adopt a persona alters the representational geometry of the model's latent space. We extract representations of over 9,000 common words and 33 semantic axes from models adopting liberal and conservative political personas and compare these against two neutral baselines. We find that persona conditioning systematically alters both the projections of words onto semantic axes and the alignments among the axes themselves in directions consistent with the specified ideology. We then test the implications of this reorganization for two safety-relevant features: truthfulness and morality. Linear probes, SAE-based classifiers, and classifiers built from manually selected word representations, all trained without a persona, produce divergent results when applied to models conditioned on political personas, producing politically slanted ratings of truth and morality on controversial statements. These findings suggest that internal representations, as they are conventionally extracted, can exhibit different geometric relations when the model adopts personas, potentially undermining monitoring efforts.
#05Nov 4, 2026
cs.AI
On Turn-Level Best-of-N Sampling for Scaling LLM Agents
Jalaj Bhandari, Dhawal Gupta, Hongli Zhan and 5 more
In this work, we evaluate a simple inference-time scaling approach based on \textit{turn-level best-of-N sampling} (\method) for large language model (LLM) agents on complex, long-horizon tasks. We instantiate this using a \textit{generator-selector} framework with two LLMs; at each turn, a \emph{generator} model generates $N$ candidate actions and a \emph{selector} model selects one of them, which is then executed in the environment. This paper is closely related to the work of \cite{zainullina2025guided} who used critic models for guided search at inference time. Different from their work, we evaluate if off-the-shelf, open-weight LLMs can be effective at comparing different candidate actions directly. Experiments on long-horizon terminal tasks show that \method can lead to significant performance improvements, both in terms of accuracy (5--10\%) and consistency across repeated attempts. Analysis of agent trajectories reveal a shift in agent behaviour towards desirable patterns such as reduction in number of attempts to solve the task, improved task instruction following, debugging and testing.