#01Aug 17, 2026
cs.CV
Can Unsupervised Methods Outperform Supervised Deep Learning When Ground Truth Is Sparse? A Case Study of Bronchovascular Bundle Segmentation in Low-Dose CT
Anna Mrukwa, Marek Socha, Aleksandra Suwalska and 9 more
Background Lung cancer remains the deadliest cancer worldwide because it is often diagnosed too late. Effective treatment depends on detection at an early screening stage. However, the growing number of patients and the limited number of radiologists lead to prolonged diagnostic waiting times. In very early stage lung cancer, nodule visibility is further reduced by adjacent blood vessels and airway walls, because nodules are often connected to or supplied by these structures. Task-specific analysis of the bronchovascular bundle is therefore important for efficient nodule detection, and its removal can increase the diagnostic potential of lung cancer screening. Materials and Methods To assess the efficacy of the proposed method, we used series from widely utilized LDCT datasets, including the Duke Lung Cancer Screening (DLCS) dataset and the Pilot Pomeranian Lung Cancer Screening Program. The proposed bronchovascular bundle segmentation pipeline, RONALD, operates on computed tomography images and returns binary masks of vessels and bronchi located in the lung parenchyma. The method includes a preprocessing stage with lung, lobe, and mediastinum segmentation, followed by separate vessel and bronchial tree segmentation. Results The proposed pipeline segmented the bronchovascular bundle in low-dose computed tomography scans while improving nodule retention compared with other segmentation methods: from 93.98% and 90.36% to 100% in DLCS, and from 83.16% and 62.36% to 99.92% in the Pomeranian dataset. Conclusion The resulting segmentations can improve lung nodule detection in the very early stages of lung cancer.
#02Aug 17, 2026
cs.AI
Policy Iteration with Human Feedback: Bringing Post-Training RL to In-context Learning
Minh-Ha Nguyen, Cathy Shyr
Generative pretraining established reusable task representations; later work on language-based task conditioning and in-context learning showed that a fixed model could adapt its behavior from instructions and demonstrations. Policy Iteration with Human Feedback (PIHF) builds on this development and the recurrent evaluate-and-improve structure of generalized policy iteration. PIHF uses a pretrained language model as its execution substrate and moves persistent revision to a versioned natural-language policy and tool set. A language-model critic and clinical expert review complete-panel reasoning and tool-use trajectories to localize recurrent failures and form candidate revisions; the expert may reinterpret the evidence and retains authority over admission and rollback, while Recall@1 and Recall@5 validate outcomes after candidate execution. Across cumulative ablations and ultra-rare-disease benchmarks, a PIHF-derived policy improved Recall@1 in one proprietary executor and three open-weight executors spanning 3 to 49 billion active parameters. Gains were 32.7 percentage points for GPT-5.4 and 31.1 points for Qwen3.6-35B, a difference of 1.7 points. These results support the feasibility of using pretrained language models as fixed-weight execution substrates for expert-guided policy development in rare-disease diagnosis.
#03Aug 17, 2026
cs.DS
Improving the matrix multiplication exponent with modern optimization and AlphaEvolve
Emilien Dupont, Marvin Eisenberger, Borislav Kozlovskii and 7 more
The current best bounds on the matrix multiplication exponent $ω$ are obtained through a refinement of the laser method called combination loss analysis (Duan et al., 2022; Williams et al., 2024; Alman et al., 2025). In this note, we address the optimization problem at the core of this approach and propose several improvements. First, we reformulate the optimization problem allowing us to solve it in a larger setting than was previously possible. Second, we leverage recent advances in machine learning to design a new optimization algorithm for this problem. Finally, we refine the resulting optimization algorithm with AlphaEvolve. Our combined approach yields an upper bound of $ω$ < 2.371177, improving the previous best bound of 2.371339.
#04Aug 17, 2026
cs.CV
SplatGuide: Geometric Priors from 3D Gaussians for Pose-Free Novel View Synthesis
Yejun Zhang, Zihan Wang, Xu Ji and 8 more
Generating photorealistic novel views from unposed images requires both 3D geometric understanding and the ability to synthesize unseen content. A natural strategy combines feed-forward 3DGS reconstruction with multi-view diffusion. Yet prior pipelines extract at most one signal from the reconstruction, either pixel rendering or learned features, while none exploits per-Gaussian visibility for occlusion-aware reference selection. This *information disconnect* leaves renderable geometry, visibility cues, and learned features unused. SplatGuide closes this disconnect by reusing a single 3DGS scene across three complementary roles. Rendered images provide pixel-aligned geometric conditioning. Per-Gaussian source-view indices are rendered into a target-view voting map for occlusion-aware reference selection. Reconstruction tokens supply feature-level guidance via cross-attention. All three signals derive from the same reconstruction forward pass. Across RealEstate10K, DL3DV, Tanks-and-Temples, and Mip-NeRF 360, SplatGuide achieves state-of-the-art pose-free novel view synthesis. On RealEstate10K, with a moderate number of input views, it surpasses the ground-truth-pose baseline.
#05Aug 17, 2026
cs.SC
AutoSR: Automatic Symbolic Regression by Searching Research States
Kejia Zhang, Youran Sun, Xinyu Ren and 2 more
We introduce Automatic Symbolic Regression (AutoSR), a fully automated system that instantiates Research-Space Symbolic Regression by searching persistent scientific investigations rather than isolated equations. Finite, noisy data often yield numerically competitive expressions that imply very different behavior outside the observed regime, making numerical fit and syntactic complexity insufficient measures of scientific credibility. Existing approaches largely focus on improving expressions, yet the search typically retains little beyond the resulting formula and score, losing the scientific record, such as motivations and probes, that inform what to try next. AutoSR preserves this record in a \textbf{Research State}, coupling each candidate equation with the reasoning, computational evidence, and independent review developed along its branch. Proposer--reviewer agents develop these states under progressive-widening Monte Carlo tree search (PW-MCTS), which allocates computation across competing investigations, while the accumulated research record is ultimately synthesized into a final report that explains the leading relation and the basis for its selection. Across nine selected challenges from two benchmark suites, AutoSR recovers algebraically equivalent relations in every case, including three cp3-bench problems that no published system recovers and six structurally diverse LSR-Transform problems. Overall, AutoSR extends symbolic regression from equation-level search toward automated scientific investigation, allowing scientific knowledge and accumulated evidence to shape both what is explored and how the resulting equation is justified.