#01Jul 20, 2026
cs.AI
Judge-dependent safety gains and model-specific helpfulness costs of evidence-sufficiency prompting in clinical LLMs
Koyar Afrasyab
Background: LLM judges increasingly score whether clinical language models give overconfident answers under incomplete evidence, yet whether a measured "safety gain" reflects real behavior change or the judge's calibration is unresolved. Using a structured evidence-sufficiency prompt as a test case, we asked whether it reduces unsafe overconfident answers, how far that effect depends on the scoring judge, and what it costs in helpfulness. Methods: In a retrospective public-data benchmark (Real-POCQi, HealthBench, MedRBench), four models (GPT-5.5, Claude Opus 4.8, Gemini 3.5 Flash, Grok 4.3) answered a fully paired common panel (1,200 cells) with a standard prompt and the wrapper. The pre-specified endpoint was the paired reduction in unsafe overconfidence scored by the primary judge (GPT-5.4-nano); secondary analyses added a different-family judge (Claude Sonnet 5), a correctness judge, matched scaffold controls, and a blinded three-clinician review. Results: Unsafe overconfidence fell from 49.3% to 24.7%, a paired reduction of 24.7 points (95% CI 21.8-27.7; p<0.001), robust in direction across models and paraphrases. Magnitude was judge-dependent: Sonnet agreed on direction but nearly halved the effect (+13.1 points), with one-directional disagreement. Blinded clinicians characterized the primary judge as a high-sensitivity (1.00), low-specificity (0.55) screen, not a calibrated rate. The gain carried a model-specific helpfulness cost (correct diagnosis 80.3% to 50.3%): near-free for GPT-5.5, near-total for Gemini (-58 points). Matched scaffold controls showed genuine behavior change, not judge circularity. Conclusions: LLM-judged clinical safety effects should be reported as directional and relative, anchored to human review and evaluated jointly with helpfulness, not as calibrated absolute rates. This does not establish clinical deployment readiness.
#02Jul 20, 2026
cs.CL
Modeling turn-taking with distant viewing: investigating silence thresholds in human and AI-generated discourse
Taylor Arnold, Nicolas Ballier, Artem Saloev
This study investigates silence gaps in two kinds of audiovisual material. We analysed thirty US situational comedies and fifty-one synthetic podcasts generated with Google NotebookLM. Gaps were compared across speaker gender, assigned from a fundamental-frequency threshold estimated in Praat, and across production settings.
#03Jul 20, 2026
cs.CV
GigaPath-Flash and GigaTIME-Flash: Efficient Pathology Foundation Models for Whole-Slide and Tumor Microenvironment Analysis
Naoto Usuyama, Jeya Maria Jose Valanarasu, Sicong Yao and 24 more
Foundation models have emerged as a driving force in computational pathology, with the potential to transform cancer diagnosis, prognosis, and treatment selection by learning transferable representations from large-scale histopathology data. A growing landscape of pathology foundation models now spans diverse data sources, architectures, and downstream applications. However, most pretrained models operate only at the image-tile level, use restrictive licenses, and remain computationally expensive, limiting large-scale slide-level clinical and research use. Here, we introduce GigaPath-Flash and GigaTIME-Flash, efficient models for whole-slide pathology AI and spatial proteomics prediction. GigaPath-Flash combines a 22M-parameter ViT-S tile encoder with a 21M-parameter LongNet slide encoder, both pretrained on large-scale real-world histopathology data. Its compact tile encoder is distilled from the billion-parameter GigaPath (ViT-g) teacher and shared by both models. GigaPath-Flash retains 97% of GigaPath's average slide-level performance with 50x less compute. GigaTIME-Flash extends this backbone to predict the tumor immune microenvironment directly from routine H&E images. It surpasses the original CNN-based GigaTIME in prediction quality while running 6x faster and using 8x less GPU memory. Together with GigaPath and GigaTIME, these models form an open-weight, Apache-2.0-licensed family pretrained on large-scale real-world clinical data. By releasing all models and weights, we provide accessible building blocks for computational pathology, immuno-oncology, and precision health.
#04Jul 20, 2026
cs.AI
Logical Judgments Under Pressure: Diagnosing Syllogistic Stability with Learned Soft Prefixes
Brian K Chen
To test how correct logical judgments respond to learned context, we prepend a soft prefix to an exactly labeled syllogistic reasoning benchmark while keeping the model fixed. Soft prefixes are opaque continuous vectors, so we characterize them through the behavior they induce across controlled variations in logical form and interface. By studying which prefixes succeed and how their effects generalize, we characterize how learned contextual pressure can override correct judgments and expose limits in a model's logical stability. Across Qwen3.6-35B-A3B MoE, Qwen3-8B, and Gemma 4 31B, learned prefixes redirect many correct answers and remain effective across unseen forms and interface changes. In repeated tests with Qwen3.6 MoE and Gemma, they outperform paired random controls in all 16 model--direction--split comparisons by 37 to 99 percentage points. Qwen3.6 MoE flip rates remain between 72% and 90% across wording and prompt changes, while Gemma validity prefixes retain 54% to 56% flip compared with less than 1% for matched random prefixes. Diagnostic tests show that the dominant effect is a broad preference for one answer meaning rather than fixed-symbol forcing or a logical operation that transfers reliably between tasks. The form of this bias differs across models. In both Qwen models, simple score models often predict which judgments will flip but not how far their margins will move, whereas Gemma's overall response is more closely approximated by the same models. These results show that the dominant behavioral effect of successful soft prefixes is a broad answer preference, while the remaining response reveals substantial model-specific differences in logical stability.
#05Jul 20, 2026
cs.LG
A Continual Validation, Updating, and Decision-Making Framework for Self-Adaptive Digital Twins via Robust Model Predictive Control: A Case Study in Additive Manufacturing
Yi-Ping Chen, Ying-Kuan Tsai, Vispi Karkaria and 3 more
Digital Twins rely on surrogate models to mirror physical systems in real time, yet these models can degrade as operating conditions evolve, a phenomenon known as concept drift. Maintaining surrogate fidelity under drift, particularly when models must also capture aleatoric uncertainty, remains an open challenge. Existing adaptive frameworks lack principled mechanisms for detecting when updates are needed, for efficiently adapting models from limited streaming data, and for certifying that updates genuinely improve predictive performance. Here we present an adaptive Digital Twin framework that integrates a Fisher score--based multivariate drift detector, Low-Rank Adaptation (LoRA) for parameter-efficient continual learning, and a Mann--Whitney $U$ test for online statistical validation. The framework monitors surrogate-model confidence via Fisher score vectors, triggers targeted fine-tuning of fewer than 1% of model parameters upon drift detection, and statistically certifies predictive improvement before deploying the updated surrogate. Applied to a stochastic linear system and a directed energy deposition additive manufacturing process as case studies, the framework successfully detects distributional shifts with short delays and restores both predictive accuracy and uncertainty quantification under abrupt and incremental drift. These results establish a statistically rigorous and computationally tractable pathway for sustaining the trustworthiness of neural-network--based Digital Twins throughout their operational life cycle.